NewSelf Tirzepatide Pricing at a Glance
the NewSelf program's Tirzepatide Plus⁺ is priced at $144.49/month on the dedicated product page — making it the most aggressively priced compounded tirzepatide from any major US telehealth platform tracked as of September 2026.
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| Provider | Tirzepatide/Mo | Mechanism | All Doses Same? |
|---|---|---|---|
| NewSelf (promo) | $144.49 | Compounded GLP-1/GIP | Yes |
| GobyMeds | ~$249 | Compounded GLP-1/GIP | Varies |
| Zepbound (brand, no ins) | $1,059+ | FDA-approved GLP-1/GIP | No |
| Hims & Hers | Not offered | N/A | N/A |
Why Tirzepatide Costs More Than Semaglutide
The $44.52/month premium over NewSelf's GLP-1 platform semaglutide reflects: (1) higher pharmaceutical active ingredient cost — tirzepatide is a more complex molecule than semaglutide; (2) broader dosage range requiring wider preparation variability (2.5mg–15mg); and (3) generally higher market price across the compounded GLP-1 sector. The premium is consistent across all providers.
Is It Worth $144.49 vs $99.97 for Semaglutide?
SURMOUNT-1 data shows tirzepatide achieves 22.5% average weight loss vs semaglutide's 15% — a 7.5 percentage point difference that, on a 220 lb individual, translates to 16.5 lbs more weight lost on average. Over a 6-month program, the total tirzepatide premium is ~$267. Dividing the extra cost by the extra expected weight lost: the premium is often justified for patients with significant weight-loss goals. See our full mechanism comparison.